FORMULASI DAN KARAKTERISASI HIDROGEL EKSTRAK DAUN DADAP SEREP (Erythrina folium) DALAM BENTUK PLESTER SEBAGAI PENURUN DEMAM

ever is a condition where body temperature is more than 37.5oC, fever can also be an early clinical
manifestation
of a certain infection. Efforts to overcome the fever begins with self
-
medication that is with
symptomatic treatment. Dadap plant is a plant that examines many properties as traditional medicine, but this plant
can only be found in certain regions.
Object
ive
: To determine whether the extract of Dadap's leaves (Erythrina
folium) can reduce fever temperature when formulated in the form of hydrogels.
Method
: The population in this
study was hydrogel leaf extract dadap spare. This research was carried out by m
aking three hydrogel formulas of
Dadap leaf extract spare with a composition of every 30 g of preparations containing F1 Dadap leaf extract for 2.5
g; F2 for 5 g, and F3 for 10 g. From the three formulas, the physical properties of the hydrogel were analyz
ed to see
the characterization of the hydrogel which included organoleptic test, pH test, viscosity test, homogeneity test and
temperature drop test in mice test animals.
Results
: The results of the research of the three hydrogel formula
extracts of Dadap
leaves, F1, F2 and F3 have the same characterization, namely semi
-
solid form, distinctive odor
and green color, pH of hydrogel which is 6.0
-
6.5, viscosity 170,000
-
236,000 cP and homogeneous. In the test of
temperature reduction with mice test animals effec
tive in formulas F2 and F3, namely the Dadap leaf extract
hydrogel with the composition of every 30 g of preparations containing leaf extracts with dadap 5 g and 10 g.
Conclusions and suggestions
: Extract hydrogel formulations have different characterizati
ons. From the three
hydrogel formulations, Dadap leaf extract which can reduce the effective temperature is F2 and