PERBANDINGAN UJI MUTU TABLET HISAP VITAMIN C MEREK “X” DENGAN DUA VARIAN RASA DI SALAH SATU APOTEK DI KECAMATAN PONOROGO

Vitamin C lozenges are drugs circulating in pharmacies and in stores. Many people who
consume vitamin C lozenges because it has a function as the body's defense. The diffe
rence in taste in
vitamin C lozenges also needs to be well known.
Objectives
:
The purpose of this study was to determine
whether or not there were differences in the taste variance that affected the quality of vitamin C lozenges
in terms of chemical analysi
s and physical analysis based on the requirements set by Indonesian
Pharmacopoeia.
Methods:
The sampling technique used in this research
.
Parameters for testing the
quality of lozenges were weight test, friability/friability /fragility test of tablets, tabl
et hardness test, size
uniformity test, weight variability test, and active substance level. In the test of determining the levels of
active substances with the Iodimetry method. Hypothesis testing using Independent T Test statistical
test.
Results:
The res
ults showed that the sample quality test for lemon and strawberry flavors in terms of
six parameters met the requirements that had been set. The results of each quality test meet the
requirements and test levels obtained the value of T count 0.584 at equal
variances assumed and T table
2.306 has a significant value of 0.575 meaning greater than 0.05, then H0 is accepted which means there
is no difference in vitamin C levels in the two variants taste. The requirements used in the assay, weight
variation, wei
ght uniformity, size uniformity are listed in the Indonesian Pharmacopoeia, for the
requirements for hardness and brittleness testing listed in the pharmaceutical industry
requirements.
Conclusions and suggestions:
The results of chemical and physical analy
sis with two
variations of taste did not give a difference in the quality of the tablets. Expected to be more careful in
choosing a drug and pay attention to how it is stored