2017.“Penetapan Kadar Natrium Klorida (NaCl) Dalam Sediaan Infus Merek “A, B, C” Dengan Menggunakan Metode Argentometri Mohr”

Infusion Sodium Chloride is a sterile preparation of a solution or emulsion, pyrogen free and as much as possible isotonic to blood, injected directly into the vein in a relatively large volume. Intravenous infusion is not allowed to contain bactericide and buffer substances. Solutions for intravenous infusion should be clear and practically particle free. Infusion is widely used by inpatients, as it can be used to provide or replace body fluids containing water, electrolytes, vitamins, fats and calories, which can not be maintained strongly through oral, improves acid-base balance, improves the volume of blood components, Entrance for the administration of drugs into the body. The purpose of this study was to determine the level of NaCl terrdapat on samples infus "A, B, C". And whether the three infusion samples meet the requirements listed in Pharmacope Indonesia Edition V 2014.
Testing of three brands of infusion taken from three pharmacies in ponorogo.This research was conducted on sodium chloride infusion and analyzed the level using mohr argentometric method that is method to determine chloride level in neutral atmosphere with standard solution of silver nitrate with addition of potassium chromate solution as indicator of this research done In the laboratory Akafarma Sunan Giri Ponorogo.
Based on the result of the research, it can be concluded that the sodium chloride content of A sample infusion of 0.910%, B of 0.894% and C of 0.893% fulfill the requirements stated in Pharmacope Indonesia Edition V of 2014 which is not less than 95.0% and not more Of 105.0% NaCl of the amount indicated on the label.
Keywords: Sodium Chloride, Infusion Liquid, Argentometry Mohr