“Optimasi Formula Gel Ekstrak Kulit Batang Turi (Sesbaniae cortex) dan Uji Aktivitas pada Candida albicans ATCC 10231 dan Staphylococcus aureus ATCC 25923”.

Sprue is a common oral mucosal disease. Sprue can be treated in various
ways, both traditional and modern. In general, traditional methods of treatment for
canker sores are considered to be less effective and efficient. Efforts should be
made to create new innovatios in preparations that can provide comfort and ease
of use with gel preparations made with natural ingredients, namely turi bark which
is efficacious in treating sprue. The formulation of the problem raised is whether
the gel preparations from the bark extract (Sesbaniae cortex) can fulfill the
physical evaluation and how the Sesabniae cortex extract gel activity inhibits the
growth of Candida albicans ATCC 10231 and Staphylococcus aureus ATCC
25923.
The products studied were turi bark extract gel preparations consisting of
three formulas with a composition of extracts of 1%, 3%, and 5%. And tested the
physical evaluation consisting of organoleptic test, homogeneity test, pH test, and
scattering power test. Accompanied by an activity test for Candida albicans
ATCC 10231 and Staphylococcus aureus ATCC 25923. Calculation of the
inhibition zone around the paper disc in the activity test way analyzed using One
Way ANOVA.
The results of the study evaluating the physical gel of the turi bark extract
of the three formulas fulfilled the requirements. Organoleptic test produce
different colors of each formula, distinctive smell, and have a half-solid texture.
The homogeneity test shows the three homogeneous formulas. The pH test and
the scattering power test of three formulas had the pH and spreadability that met
the requirements. The activity test showed that the greater the concentration of turi
bark extract, the greater the inhibition zone produced.